Read The Studies 

Our work is supported by science-backed, peer-reviewed research. These studies examine the role of Effector Proteins in regulating inflammatory pathways and their potential impact on chronic skin concerns.

  • bioRxiv

    05/09/2026

    A Yersinia effector activates JAK-STAT signaling in human macrophages.  Berneking, L., Schnapp, M., Rumm, A., Trasak, C., Ruckdeschel, K., Alawi, M., & Grundhoff, A. 
    Read the study
  • Cellular and Molecular Life Sciences

    07/09/2013

    Autonomous translocation and intracellular trafficking of the cell-penetrating
    and immune-suppressive effector protein YopM.
    Scharnert, J., Greune, L.,
    Hirota, K., Fuhrmann, O., Heusipp, G., Schmidt, M. A., & Rüter, C.
    Read the study
  • International Journal of Medical Microbiology

    05/04/2015

    Current activities of the Yersinia effector protein YopM.
    Höfling, S., Grabowski, B., Norkowski, S., Schmidt, M. A., & Rüter,
    C.
    Read the study
  • Journal of Cell Science

    06/09/2010

    A newly identified bacterial cell-penetrating peptide that reduces the transcription of pro-inflammatory cytokines.
    Rüter, C., Buss, C., Scharnert, J., Heusipp, G., & Schmidt, M. A.
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  • Virulence

    07/03/2017

    Immunomodulatory Yersinia outer proteins (Yops)–useful tools for bacteria and humans alike.
    Grabowski, B., Schmidt, M. A., & Rüter, C.
  • Virulence

    05/15/2014

    Manipulation of pro-inflammatory cytokine production by the bacterial cell-penetrating effector protein YopM is independent of its interaction with host cell kinases RSK1 and PRK2. Höfling, K., Höfling, C., Hilbig, A., Berneking, L., Ruckdeschel, K., & Aepfelbacher, M.
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